Article
Histiocytes in familial and infection-induced/idiopathic hemophagocytic syndromes may exhibit phenotypic differences.
Pediatric pathology - 1 Jan 2000
Buckley P J, O'Laughlin S, Komp D M
Abstract excerpt
Familial hemophagocytic syndrome (FHS) and infection-associated hemophagocytic syndrome (IAHS) usually present with fever, pancytopenia, hepatosplenomegaly, signs of hepatic dysfunction, bleeding diathesis, and neurological manifestations. FHS is almost uniformly fatal, and IAHS is associated wit...
Topics
- Adolescent
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- CD11 Antigens
- Female
- Histiocytes
- Histiocytosis, Non-Langerhans-Cell
- Humans
- Immunoenzyme Techniques
- Immunohistochemistry
- Immunophenotyping
- Infant
- Infant, Newborn
- Macrophages
- Male
- Phenotype
- Receptors, Complement