Article
New developments in the molecular epidemiology of adenovirus 8 keratoconjunctivitis.
Journal of medical virology - 1 Oct 1992
de Jong J C, Démazure M, Legrand-Quillien M C, Le Lay G, Colin J, Wermenbol A G, Verweij-Uÿterwaal M W, van der Avoort H G, Chastel C
Abstract excerpt
Four consecutive epidemics of keratoconjunctivitis caused by adenovirus 8 (Ad8) occurred over a 5-year period in Brest, France. A selection of 30 strains isolated during this period was studied by DNA restriction enzyme analysis using nine restriction enzymes. BglI and SacI were the most discriminative enzymes and allowed the recognition of four DNA variants, all different from the prototype strain Trim. Within...
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