Article
Nasal T-cell lymphoma associated with hemophagocytic syndrome. Immunohistochemical and genotypic studies.
Archives of pathology & laboratory medicine - 1 Nov 1992
Chubachi A, Imai H, Nishimura S, Saitoh M, Miura A B
Abstract excerpt
A 53-year-old man with nasal T-cell lymphoma exhibited hemophagocytic syndrome as a terminal event. Immunohistochemical studies revealed that neoplastic cells were derived from T cells. Genotypic analysis of DNA samples that were obtained from the frozen tissue specimens demonstrated clonal rearrangements of the T-cell receptor beta-chain genes. No rearrangement was observed in the immunoglobulin heavy-chain...
Topics
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genotype
- Histiocytes
- Histiocytosis, Non-Langerhans-Cell
- Humans
- Immunohistochemistry
- Liver
- Lymphoma, T-Cell
- Male
- Middle Aged
- Nasal Cavity
