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Article

Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and comparison with vaccinia virus.

The Journal of general virology - 1 Nov 1992

Aguado B, Selmes I P, Smith G L

Abstract excerpt

A 21.8 kbp region of the genome of variola major virus (strain Harvey), a virus that caused haemorrhagic-type smallpox, has been sequenced and shown to possess 96% nucleotide identity to the corresponding region of vaccinia virus, the smallpox vaccine. Overall the gene arrangement in the two viruses is highly similar and individual open reading frames (ORFs) display a high degree of amino acid identity, for...

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PMID: 1331292
DOI: 10.1099/0022-1317-73-11-2887

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