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Article

Activation of a cryptic streptomycin-resistance gene in the Bacteroides erm transposon, Tn4551.

Molecular microbiology - 1 Aug 1992

Smith C J, Owen C, Kirby L

Abstract excerpt

Bacteroides compound transposons encoding erm resistance are highly homologous but previous studies have shown some divergence of Tn4551. Results presented here describe a novel Tn4551 streptomycin-resistance gene, aadS, that was phenotypically silent in wild-type Bacteroides. However, aadS expression could be activated by a trans-acting chromosomal mutation. The aadS-encoded peptide displayed significant...

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PMID: 1328814
DOI: 10.1111/j.1365-2958.1992.tb01404.x

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