Article
Latency and reactivation of a thymidine kinase-negative bovine herpesvirus 1 deletion mutant.
Archives of virology - 1 Jan 1992
Whetstone C A, Miller J M, Seal B S, Bello L J, Lawrence W C
Abstract excerpt
A bovine herpesvirus 1 (BHV 1) mutant variant with a deletion in the thymidine kinase (TK) gene was assessed for its ability to establish latency and be reactivated in cattle. After treatment with dexamethasone, reactivated TK- BHV 1 was isolated from one of four cattle that received virus by intravenous inoculation only, and from four of four cattle that received virus by intranasal, intravaginal, and...
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