Article
Frequency and distribution of phenylketonuric mutations in Orientals.
Human mutation - 1 Jan 1992
Okano Y, Hase Y, Lee D H, Furuyama J, Shintaku H, Oura T, Isshiki G
Abstract excerpt
The frequency and distribution of eight mutations (R111X, IVS4nt-1, Y204C, R243Q, IVS7nt-2, W326X, Y356X, and R413P) in the phenylalanine hydroxylase gene of Orientals in Japan and Korea were examined by allele-specific oligonucleotide hybridization. The mutant alleles comprised 54 and 55% of the...
Topics
- Alleles
- Asian People
- China
- DNA Mutational Analysis
- Gene Frequency
- Humans
- Japan
- Korea
- Mutation
- Nucleic Acid Hybridization
- Phenylketonurias
- Polymerase Chain Reaction