Article
Trisomy of the short arm of chromosome 4: the changing phenotype with age.
Annales de genetique - 1 Jan 1992
Kleczkowska A, Fryns J P, van den Berghe H
Abstract excerpt
In this paper the authors describe three patients with trisomy of the short arm of chromosome 4 with special attention to the striking phenotypic changes with age. When they get older the round face with chubby cheeks, deeply-set eyes and broad and flat nasal root with a bulbous nose tip becomes...
Topics
- Aging
- Child
- Chromosomes, Human, Pair 4
- Face
- Female
- Growth Disorders
- Humans
- Infant, Newborn
- Intellectual Disability
- Karyotyping
- Male
- Pedigree
- Phenotype
- Psychomotor Disorders
- Trisomy