Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population genetics of hereditary hemochromatosis in Saguenay Lac-Saint-Jean (Quebec, Canada).

Annales de genetique - 1 Jan 1992

de Braekeleer M, Vigneault A, Simard H

Abstract excerpt

Hereditary hemochromatosis (HH) is an autosomal recessive disorder that has a high prevalence in Caucasian populations. Based on HLA typing in 18 families, the gene frequency was estimated 0.12. The homozygote frequency was 0.014 and the heterozygote frequency was 0.21 in Saguenay Lac-Saint-Jean (SLSJ), a geographically isolated region of northeastern Quebec. The genealogical reconstruction showed that 15 of the...

Topics

Consanguinity
Female
Gene Frequency
Genes, Recessive
Genotype
Hemochromatosis
Humans
Male
Pedigree
Prevalence
Quebec

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1296515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1296515-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population genetics of hereditary hemochromatosis in Saguenay Lac-Saint-Jean (Quebec, Canada).PMID 1296515Read ↗

Portrait of autosomal recessive diseases in the French‐Canadian founder population of Saguenay‐Lac‐Saint‐JeanSemantic proximity Read ↗

Variability of the genetic contribution of Quebec population founders associated to some deleterious genes.Semantic proximity Read ↗

Clinical and molecular aspects of juvenile hemochromatosis in Saguenay-Lac-Saint-Jean (Quebec, canada).Semantic proximity Read ↗

Genetic consequences of differential demographic behaviour in the Saguenay region, Québec.Semantic proximity Read ↗

Mutation analysis in the HFE gene in patients with hereditary haemochromatosis in Saguenay-Lac-Saint-Jean (Quebec, Canada).Semantic proximity Read ↗

Genealogy and geographical distribution of CFTR mutations in Saguenay Lac-Saint-Jean (Quebec, Canada).Semantic proximity Read ↗

Human Genetics: Lessons from Quebec PopulationsSemantic proximity Read ↗

Evolution of inbreeding coefficients and effective size in the population of Saguenay Lac-St.-Jean (Quebec).Semantic proximity Read ↗

A registry-based population study of the HLA in Québec, Canada.Semantic proximity Read ↗

Population genetics of vitamin D‐dependent rickets in northeastern QuebecSemantic proximity Read ↗

High Frequency of Hb E-Saskatoon (HBB: c.67G > A) in Brazilians: A New Genetic Origin?Semantic proximity Read ↗

[Genealogical study of oculopharyngeal dystrophy at Saguenay-Lac-St-Jean, Quebec, Canada].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.