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Article

Kinetic and physical characterisation of recombinant wild-type and mutant human protoporphyrinogen oxidases.

Biochimica et biophysica acta - 21 Aug 2003

Maneli Mbulelo H, Corrigall Anne V, Klump Horst H, Davids Lester M, Kirsch Ralph E, Meissner Peter N

Abstract excerpt

The effects of various protoporphyrinogen oxidase (PPOX) mutations responsible for variegate porphyria (VP), the roles of the arginine-59 residue and the glycines in the conserved flavin binding site, in catalysis and/or cofactor binding, were examined. Wild-type recombinant human PPOX and a sele...

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Source

Identifiers

PMID: 12922165
DOI: 10.1016/s1570-9639(03)00186-9

Genes

PPOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12922165-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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