Article
[Prevention of adverse reactions of antituberculous drugs in pulmonary tuberculosis in patients with different genetic background].
Problemy tuberkuleza i boleznei legkikh - 1 Jan 2003
Tashpulatova F K
Abstract excerpt
To study genetic predisposition to adverse reactions caused by drugs, 367 patients with pulmonary tuberculosis were examined. As a genetic marker, the phenotype of haptoglobin (Hp) carriage, the type of HINC inactivation, the activity of the enzyme G-6-PDHG were determined. Adverse reactions were noted in 60.2% of the patients. If there was an unfavourable combination of genetic markers, adverse reactions...
Topics
- Antitubercular Agents
- Genetic Markers
- Genotype
- Humans
- Phytotherapy
- Tuberculosis, Pulmonary
