Article
Factor V Leiden mutation and its relation to left atrial thrombus in chronic nonrheumatic atrial fibrillation.
Japanese heart journal - 1 Jul 2003
Gökçe Mustafa, Uçar Fahri, Küçükosmanoglu Mehmet, Erdoğan Turan, Kaplan Sahin
Abstract excerpt
The genetic defect of coagulation factor V, known as factor V Leiden, produces a resistance to degradation by activated protein C and increased venous thrombosis. However, the role of factor V Leiden in the formation of left atrial thrombus with nonrheumatic atrial fibrillation has not been studied. We investigated whether factor V Leiden is a risk factor for left atrial thrombus in patients with nonrheumatic...
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