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Problematic Variation in Local Institutional Review of a Multicenter Genetic Epidemiology Study

15 Jul 2003

Abstract excerpt

CONTEXT: Sequencing of the human genome provides an immense resource for studies correlating DNA variation and epidemiology. However, appropriately powered genetic epidemiology studies often require recruitment from multiple sites. OBJECTIVES: To document the burden imposed by review of multicenter studies and to determine the variability among local institutional review boards (IRBs) in the approval of a...

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PMID: 12865377
DOI: 10.1001/jama.290.3.360

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