Article
Forms of mineralocorticoid hypertension.
Vitamins and hormones - 1 Jan 2003
Ferrari Paolo, Bonny Olivier
Abstract excerpt
Hypertension with hypokalemia, metabolic alkalosis, and suppressed plasma renin activity defines mineralocorticoid hypertension. Mineralocorticoid hypertension is the consequence of an overactivity of the epithelial sodium channel expressed at the apical membrane of renal cells in the distal nephron. This is usually the case when the mineralocorticoid receptor is activated by its physiologic substrate...
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