Article
[Respiratory allergic disease genes].
Revue de pneumologie clinique - 1 Apr 2003
Demoly P
Abstract excerpt
Asthma and atopy are polygenic diseases with an hereditary and an environmental component. Improvement in statistical and molecular tools has enabled the localization of a dozen chromosome regions bearing susceptibility genes: 1p32-34, 3q21, 5q31-33, 6p21-23, 11p15, 11q13, 12q14-24, 13q14-qter, 14q11, 17q11-21, 19q13 and 20p13. There are many candidate genes, particular the cluster of interleukin-4 genes...
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