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Folate uptake in the human intestine: Promoter activity and effect of folate deficiency

10 Jun 2003

Abstract excerpt

The intestinal folate absorption process occurs via a specialized mechanism that involves the reduced folate carrier (RFC). In humans, multiple variants of the hRFC (driven by multiple promoters) have been identified with variant I being the prominent form expressed in the intestine. While it is known that promoter B (pB) of hRFC drives the expression of this variant, little is known about the minimal region...

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PMID: 12811835
DOI: 10.1002/jcp.10324

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