Article
Influence of tat mutations on the ribose-binding protein translocation in Escherichia coli.
Biochemical and biophysical research communications - 4 Jul 2003
Pradel Nathalie, Santini Claire-Lise, Ye Chang-Yun, Fevat Léna, Gérard Fabien, Alami Meriem, Wu Long-Fei
Abstract excerpt
Proteins are exported across the bacterial cytoplasmic membrane either as unfolded precursors via the Sec machinery or in folded conformation via the Tat system. The ribose-binding protein (RBP) of Escherichia coli is a Sec-pathway substrate. Intriguingly, it exhibits fast folding kinetics and its export is independent of SecB, a general chaperone protein dedicated for protein secretion. In this study, we found...
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