[Polymorphism MI detected through the enzyme MspI in the study of congenital protein C deficiency].

Article

[Polymorphism MI detected through the enzyme MspI in the study of congenital protein C deficiency].

Medicina clinica - 21 Nov 1992

Soria J M, Ibáñez I, Fontcuberta J, Borrell M, Estivill X, Sala N

Abstract excerpt

BACKGROUND: In order to find alternatives for the diagnosis of hereditary protein C (PC) deficiency, we have studied the diagnostic informativity of the restriction fragment length polymorphism (RFLP) MI, located 7 kb upstream of the PC gene and detected with the restriction enzyme MspI. METHODS:...

Topics

Alleles
Blood Coagulation Disorders
Carrier State
DNA
Deoxyribonuclease HpaII
Deoxyribonucleases, Type II Site-Specific
Female
Humans
Polymorphism, Genetic
Pregnancy
Prenatal Diagnosis
Protein C Deficiency

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