Article
Inactivation of the nod box distal half-site allows tetrameric NodD to activate nodA transcription in an inducer-independent manner.
Nucleic acids research - 15 Jun 2003
Feng Jie, Li Qiang, Hu Hai-Liang, Chen Xiao-Chun, Hong Guo-Fan
Abstract excerpt
In Rhizobium leguminosarum, NodD can activate nodA transcription in response to inducer flavonoids. Here, we show that the inducible nodA promoter contains an intrinsic part through which NodD can activate nodA transcription in an inducer-independent manner. Evidence was provided that NodD binds to target DNA through anchoring the two half-sites of the nod box as a tetramer. An imperfect inverted repeat...
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