Article
I/D ACE gene polymorphism in survival of leukemia patients -- hypothesis and pilot study.
Medical hypotheses - 1 Jul 2003
Hajek Dobroslav, Tomiska Miroslav, Krahulcova Eva, Druckmuller Miloslav, Florianova Michaela, Izakovicova-Holla Lydie, Vacha Jiri
Abstract excerpt
Angiotensin-I converting enzyme (ACE) is involved not only in intracellular volume regulation but also in proliferation control. Since both ACE gene polymorphism (I/D ACE) and ABO blood group determine ACE level in peripheral blood and probably also in bone marrow, the hypothesis to the interindividual differences in survival of leukemic patients was suggested. The data of 25 patients of both sexes with acute...
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