Article
Genomics and proteomics in cancer.
European journal of cancer (Oxford, England : 1990) - 1 Jun 2003
Baak J P A, Path F R C, Hermsen M A J A, Meijer G, Schmidt J, Janssen E A M
Abstract excerpt
Cancer development is driven by the accumulation of DNA changes in the approximately 40000 chromosomal genes. In solid tumours, chromosomal numerical/structural aberrations are common. DNA repair defects may lead to genome-wide genetic instability, which can drive further cancer progression. The...
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