Article
Genetic predisposition to external apical root resorption in orthodontic patients: linkage of chromosome-18 marker.
Journal of dental research - 1 May 2003
Al-Qawasmi R A, Hartsfield J K, Everett E T, Flury L, Liu L, Foroud T M, Macri J V, Roberts W E
Abstract excerpt
External apical root resorption (EARR) is a common orthodontic treatment sequela. Previous studies implicate a substantial genetic component for EARR. Using a candidate gene approach, we investigated possible linkage of EARR associated with orthodontic treatment with the TNSALP, TNFalpha, and TNFRSF11A gene loci. The sample was comprised of 38 American Caucasian families with a total of 79 siblings who completed...
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