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Article

Metabolism of phytanic acid and 3-methyl-adipic acid excretion in patients with adult Refsum disease.

Journal of lipid research - 1 Aug 2003

Wierzbicki Anthony S, Mayne Phillip D, Lloyd Matthew D, Burston David, Mei Guam, Sidey Margaret C, Feher Michael D, Gibberd F Brian

Abstract excerpt

Adult Refsum disease (ARD) is associated with defective alpha-oxidation of phytanic acid (PA). omega-Oxidation of PA to 3-methyl-adipic acid (3-MAA) occurs although its clinical significance is unclear. In a 40 day study of a new ARD patient, where the plasma half-life of PA was 22.4 days, omega-...

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PMID: 12700346
DOI: 10.1194/jlr.M300121-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12700346-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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