Article
Identification of a novel allele HLA-B*5610 in a Chinese potential bone marrow donor.
Tissue antigens - 1 Mar 2003
Wu G-G, Cheng L-H, Zhou D, Deng Z-H, Zou H-Y, Wei T-L, Li Z, Li D-C, Gao S-Q, Zhao T-M
Abstract excerpt
A novel HLA-B allele, B*5610, has been identified in a potential bone marrow donor, his mother and brother using DNA-based typing and molecular cloning methods. The B*5610 allele differs from the closest matching HLA sequence of B*5602 by two nucleotide substitutions in exon 3, 559 C-->A and 560 T-->C, resulting in an amino acid change from Leu (CTG) to Thr (ACG) at codon 187. This new allele was segregated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
