Wolbachia-Induced Mortality as a Mechanism to Modulate Pathogen Transmission by Vector Arthropods

Abstract excerpt

Insecticide resistance and absence of clinical cures or vaccines for many vector-borne diseases has stimulated interest in using genetically modified arthropod vectors for disease control. Current transgenic strategies focus on vector susceptibility to pathogen infection, which is an inefficient target for pathogen transmission interference. Manipulation of vector survival is theoretically more effective,...

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