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Article

Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina.

Eukaryotic cell - 1 Apr 2003

Dementhon Karine, Paoletti Mathieu, Pinan-Lucarré Bérangère, Loubradou-Bourges Nathalie, Sabourin Martine, Saupe Sven J, Clavé Corinne

Abstract excerpt

In filamentous fungi, a programmed cell death (PCD) reaction occurs when cells of unlike genotype fuse. This reaction is caused by genetic differences at specific loci termed het loci (for heterokaryon incompatibility). Although several het genes have been characterized, the mechanism of this cell death reaction and its relation to PCD in higher eukaryotes remains largely unknown. In Podospora anserina, genes...

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Identifiers

PMID: 12684373
DOI: 10.1128/EC.2.2.238-246.2003
PMCID: PMC154840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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