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The amelogenin loci span an ancient pseudoautosomal boundary in diverse mammalian species

2 Apr 2003

Abstract excerpt

The mammalian amelogenin (AMEL) genes are found on both the X and Y chromosomes (gametologous). Comparison of the genomic AMEL sequences in five primates and three other mammals reveals that the 5' portion of the gametologous AMEL loci began to differentiate in the common ancestor of extant mammals, whereas the 3' portion differentiated independently within species of different mammals. The boundary is marked by...

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PMID: 12672962
DOI: 10.1073/pnas.0635848100

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