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Article

Can defects in transferrin receptor 2 and hereditary hemochromatosis genes account for iron overload in HbH disease?

Blood cells, molecules & diseases - 1 Jan 2000

Chan Vivian, Wong Man Sim, Ooi Clara, Chen F E, Chim C S, Liang R H S, Todd D, Chan T K

Abstract excerpt

Iron overload was found to be the major cause of disability in Chinese HbH disease patients although they were not on regular blood transfusion. The transferrin receptor 2 (TFR2) and hereditary hemochromatosis (HFE) genes were examined to see if inheritance of these gene defects may be a possible...

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Source

Identifiers

PMID: 12667993
DOI: 10.1016/s1079-9796(03)00013-5

Genes

HFE
TFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12667993-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Can defects in transferrin receptor 2 and hereditary hemochromatosis genes account for iron overload in HbH disease?PMID 12667993Read ↗

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