Article
Neutralizing epitopes specific for influenza B virus Yamagata group strains are in the 'loop'.
The Journal of general virology - 1 Apr 2003
Nakagawa Naoko, Kubota Ritsuko, Nakagawa Toshimasa, Okuno Yoshinobu
Abstract excerpt
To study the neutralizing epitopes of influenza B virus Yamagata group strains, two monoclonal antibodies (mAbs) were used to select escape mutants of the virus. mAbs 5H4 and 3A12 were found to react with B/Yamagata group strains in haemagglutination inhibition and neutralization tests; no reactivity with B/Victoria group strains was observed. Most of the mutants reacted poorly to polyclonal ferret antibody...
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