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Article

Classical infantile spinal muscular atrophy with SMN deficiency causes sensory neuronopathy.

Neurology - 25 Mar 2003

Rudnik-Schöneborn S, Goebel H H, Schlote W, Molaian S, Omran H, Ketelsen U, Korinthenberg R, Wenzel D, Lauffer H, Kreiss-Nachtsheim M, Wirth B, Zerres K

Abstract excerpt

OBJECTIVE: Classic infantile spinal muscular atrophy (SMA) is believed to be a purely motor disorder, affecting neurons of the spinal anterior horn and nuclei of the lower cranial nerves. Other organ malformations or peripheral nerve involvement have been regarded as exclusion criteria for infantile SMA. Whether SMN protein deficiency can also lead to loss of sensory neurons has not been systematically addressed....

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Source

Identifiers

PMID: 12654964
DOI: 10.1212/01.wnl.0000052788.39340.45

Genes

SMN1
NAIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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