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Article

A novel splicing acceptor mutation of the factor VIII gene producing skipping of exon 25.

Annals of hematology - 1 Mar 2003

Gau J P, Hsu H C, Chau W K, Ho C H

Abstract excerpt

A gross deletion in the factor VIII (FVIII) mRNA was determined by reverse transcriptase polymerase chain reaction (RT-PCR) for a patient with moderately severe hemophilia A. Sequencing of the RT-PCR product depicted a 177-bp deletion ranging from nucleotide (nt) 6724 to nt 6900 of FVIII cDNA, exactly corresponding to the whole exon 25. Further study of the genomic DNA revealed the presence of a single base pair...

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Identifiers

PMID: 12634951
DOI: 10.1007/s00277-002-0592-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A novel splicing acceptor mutation of the factor VIII gene producing skipping of exon 25.PMID 12634951Read ↗

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