Article
[Molecular basis of heart failure and dilated cardiomyopathy].
Herz - 1 Dec 2002
Osterziel Karl Josef, Perrot Andreas
Abstract excerpt
Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure. Several prospective studies have shown that about 25-30% of all cases are of familial etiology. The most common mode of inheritance is autosomal dominant. Less frequently is inheritance as an X-chromosomal trait. Examination of families has identified nine disease genes so far. The penetrance of the identified mutations is highly variable...
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