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Article

The GLOBULAR ARREST1 gene, which is involved in the biosynthesis of folates, is essential for embryogenesis in Arabidopsis thaliana.

The Plant journal : for cell and molecular biology - 1 Jan 2003

Ishikawa Takaaki, Machida Chiyoko, Yoshioka Yasushi, Kitano Hidemi, Machida Yasunori

Abstract excerpt

We identified a mutation in Arabidopsis that resulted in defective embryos, and we designated this mutation globular arrest1 (gla1). The predicted amino acid sequence encoded by the GLA1 gene is homologous to the amino acid sequences of folylpolyglutamate synthetase (FPGS) and dihydrofolate synthetase (DHFS), which participate in folate biosynthesis. The defect of gla1 in the formation of calli was rescued by the...

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Identifiers

PMID: 12535338
DOI: 10.1046/j.1365-313x.2003.01621.x

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FPGS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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