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Article

Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death.

The EMBO journal - 2 Jan 2003

Abramovitch Robert B, Kim Young-Jin, Chen Shaorong, Dickman Martin B, Martin Gregory B

Abstract excerpt

The AvrPtoB type III effector protein is conserved among diverse genera of plant pathogens suggesting it plays an important role in pathogenesis. Here we report that Pseudomonas AvrPtoB acts inside the plant cell to inhibit programmed cell death (PCD) initiated by the Pto and Cf9 disease resistance proteins and, remarkably, the pro-apoptotic mouse protein Bax. AvrPtoB also suppressed PCD in yeast, demonstrating...

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Identifiers

PMID: 12505984
DOI: 10.1093/emboj/cdg006
PMCID: PMC140047

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