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Parental 5-methylcytosine methylation patterns are stable upon inter-species hybridization of Xiphophorus (Teleostei: Poeciliidae) fish.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Dec 2002

Li Hai-Ying, Savage Trisha, Obermoeller Rebecca D, Kazianis Steven, Walter Ronald B

Abstract excerpt

Cytosine methylation appears to be established as an important DNA base modification involved in regulation of gene expression but is poorly understood from an evolutionary viewpoint. Xiphophorus progeny from inter-species crosses and backcrosses that are utilized in contemporary tumor induction studies were analyzed for cytosine methylation pattern inheritance using Southern blot analyses. Methylation patterns...

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PMID: 12470821
DOI: 10.1016/s1096-4959(02)00166-5

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