Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A case-control comparison of the clinical characteristics of glaucoma and ocular hypertensive patients with and without the myocilin Gln368Stop mutation.

American journal of ophthalmology - 1 Dec 2002

Graul Thomas A, Kwon Young H, Zimmerman M Bridget, Kim Chang-Sik, Sheffield Val C, Stone Edwin M, Alward Wallace L M

Abstract excerpt

PURPOSE: To determine whether primary open-angle glaucoma (POAG) and ocular hypertensive (OHT) patients who harbor the myocilin Gln368Stop mutation differ in phenotype or clinical course from patients without the mutation. DESIGN: Case-control study. METHODS: A retrospective case-control study co...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Terminator
Share to Cytoskeletal Proteins
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Glycoproteins

Share to Intraocular Pressure

Share to Visual Acuity

Share to Visual Fields

Source

Identifiers

PMID: 12470758
DOI: 10.1016/s0002-9394(02)01754-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12470758-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A case-control comparison of the clinical characteristics of glaucoma and ocular hypertensive patients with and without the myocilin Gln368Stop mutation.PMID 12470758Read ↗

Clinical features associated with an Asp380His Myocilin mutation in a US family with primary open-angle glaucoma.Semantic proximity Read ↗

Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based StudiesSemantic proximity Read ↗

Evidence for genetic heterogeneity within eight glaucoma families, with the GLC1A Gln368STOP mutation being an important phenotypic modifier.Semantic proximity Read ↗

Myocilin Gln368stop mutation and advanced age as risk factors for late-onset primary open-angle glaucoma.Semantic proximity Read ↗

Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank.Semantic proximity Read ↗

A myocilin Gln368STOP homozygote does not exhibit a more severe glaucoma phenotype than heterozygous cases.Semantic proximity Read ↗

Myocilin polymorphisms and primary open-angle glaucoma: a systematic review and meta-analysis.Semantic proximity Read ↗

[Meta-analysis on the association of Myocilin Q368X mutation and primary open angle glaucoma].Semantic proximity Read ↗

Compound heterozygote myocilin mutations in a pedigree with high prevalence of primary open-angle glaucoma.Semantic proximity Read ↗

Gln48His is the prevalent myocilin mutation in primary open angle and primary congenital glaucoma phenotypes in India.Semantic proximity Read ↗

The Gly367Arg mutation in the myocilin gene causes adult-onset primary open-angle glaucoma.Semantic proximity Read ↗

Variable clinical spectrum of the myocilin Gln368X mutation in a Dutch family with primary open angle glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.