Article
Acute generalized exanthematous pustulosis: role of cytotoxic T cells in pustule formation.
The American journal of pathology - 1 Dec 2002
Schmid Simone, Kuechler Petra C, Britschgi Markus, Steiner Urs C, Yawalkar Nikhil, Limat Alain, Baltensperger Kurt, Braathen Lasse, Pichler Werner J
Abstract excerpt
Extensive formation of nonfollicular sterile pustules on erythematous background combined with fever and peripheral blood leukocytosis are the characteristics of acute generalized exanthematous pustulosis. This uncommon eruption most often is an allergic reaction because of drugs such as aminopenicillins and sulfonamides inter alia. We recently demonstrated the important role of drug-specific T cells in the...
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