Article
Origin of amnion and implications for evaluation of the fetal genotype in cases of mosaicism.
Prenatal diagnosis - 1 Dec 2002
Robinson Wendy P, McFadden Deborah E, Barrett Irene J, Kuchinka Brian, Peñaherrera Maria S, Bruyère Hélène, Best Robert G, Pedreira Denise A L, Langlois Sylvie, Kalousek Dagmar K
Abstract excerpt
OBJECTIVE: To investigate presence of trisomy in amniotic epithelium (uncultured amnion) and mesenchyme (cultured amnion) from mosaic cases to understand the origins of these tissues and their relationship to pregnancy outcome. METHODS: Polymerase chain reaction (PCR) of microsatellite loci was used to determine the presence of trisomy (of meiotic origin only) in amnion samples from 33 placentas previously...
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