Article
Molecular pathogenesis of primary hyperparathyroidism.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2002
Arnold Andrew, Shattuck Trisha M, Mallya Sanjay M, Krebs Linda J, Costa Jessica, Gallagher James, Wild Yvette, Saucier Kirsten
Abstract excerpt
This article will primarily focus on the molecular pathogenesis of common, sporadic (nonfamilial) parathyroid adenomas; two genes currently have established roles in the development of these tumors. The cyclin D1/PRAD1 gene was identified as a clonally activated oncogene in parathyroid adenomas a...
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