Article
Detection of a genetic mutation for myotonia congenita among Miniature Schnauzers and identification of a common carrier ancestor.
American journal of veterinary research - 1 Oct 2002
Bhalerao Dilip P, Rajpurohit Yashoda, Vite Charles H, Giger Urs
Abstract excerpt
OBJECTIVE: To develop a molecular genetic test to detect the mutant skeletal muscle chloride channel (CIC-1) allele that causes myotonia congenita in Miniature Schnauzers and to analyze the relationship of affected and carrier dogs. ANIMALS: 372 Miniature Schnauzers from the United States, Canada, Australia, and Europe that were tested between March 2000 and October 2001. PROCEDURE: The sequence surrounding the...
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