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Article

Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancer.

American journal of epidemiology - 15 Oct 2002

Goodman Marc T, Wu Anna H, Tung Ko-Hui, McDuffie Katharine, Cramer Daniel W, Wilkens Lynne R, Terada Keith, Reichardt Juergen K V, Ng Won G

Abstract excerpt

Deficiency in the galactose-1-phosphate uridyltransferase (GALT) enzyme results in accumulation of galactose and its metabolites in the ovary (Am J Epidemiol 1989;130:904-10). Galactose may raise gonadotropin levels, resulting in proliferation of ovarian epithelium. In 1993-1999, the authors conducted a population-based case-control study of ovarian cancer in Hawaii and Los Angeles, California, to examine the...

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Identifiers

PMID: 12370157
DOI: 10.1093/aje/kwf104

Genes

GALT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancer.PMID 12370157Read ↗

A case-control study of galactose consumption and metabolism in relation to ovarian cancer.Semantic proximity Read ↗

The N314D polymorphism of galactose-1-phosphate uridyl transferase does not modify the risk of ovarian cancer.Semantic proximity Read ↗

Galactose-1-phosphate uridyl transferase (GALT) genotype and phenotype, galactose consumption, and the risk of borderline and invasive ovarian cancer (United States).Semantic proximity Read ↗

Duarte galactose-1-phosphate uridyl transferase genotypes are not associated with ovarian cancer risk.Semantic proximity Read ↗

Mutation of galactose-1-phosphate uridyl transferase and its association with ovarian cancer and endometriosis.Semantic proximity Read ↗

Characteristics of women with a family history of ovarian cancer. I. Galactose consumption and metabolism.Semantic proximity Read ↗

Ovarian function in girls and women with GALT‐deficiency galactosemiaSemantic proximity Read ↗

No association of endometriosis with galactose-1-phosphate uridyl transferase mutations in a Chinese population.Semantic proximity Read ↗

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium.Semantic proximity Read ↗

Galactose-1-phosphate uridyl transferase gene mutations in women with premature ovarian failure.Semantic proximity Read ↗

Endometriosis associated with the N314D mutation of galactose-1-phosphate uridyl transferase (GALT).Semantic proximity Read ↗

Risk factors for premature ovarian failure in females with galactosemia.Semantic proximity Read ↗

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