Article
Evidence for a major gene influencing risk of pancreatic cancer.
Genetic epidemiology - 1 Aug 2002
Klein Alison P, Beaty Terri H, Bailey-Wilson Joan E, Brune Kieran A, Hruban Ralph H, Petersen Gloria M
Abstract excerpt
Family history of pancreatic cancer, the fifth leading cause of cancer death in the United States, confers a 1.5-13-fold higher risk of developing pancreatic cancer. Pancreatic cancer is associated with several genetic syndromes, including hereditary breast cancer (BRCA2), familial atypical multiple mole melanoma (FAMMM) syndrome, Peutz-Jeghers syndrome, hereditary pancreatitis, and hereditary nonpolyposis...
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