Article
High frequency of phenotypic deviations in Physcomitrella patens plants transformed with a gene-disruption library.
BMC plant biology - 18 Jul 2002
Egener Tanja, Granado José, Guitton Marie-Christine, Hohe Annette, Holtorf Hauke, Lucht Jan M, Rensing Stefan A, Schlink Katja, Schulte Julia, Schween Gabriele, Zimmermann Susanne, Duwenig Elke, Rak Bodo, Reski Ralf
Abstract excerpt
BACKGROUND: The moss Physcomitrella patens is an attractive model system for plant biology and functional genome analysis. It shares many biological features with higher plants but has the unique advantage of an efficient homologous recombination system for its nuclear DNA. This allows precise genetic manipulations and targeted knockouts to study gene function, an approach that due to the very low frequency of...
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