Article
Gene expression patterns in human liver cancers.
Molecular biology of the cell - 1 Jun 2002
Chen Xin, Cheung Siu Tim, So Samuel, Fan Sheung Tat, Barry Christopher, Higgins John, Lai Kin-Man, Ji Jiafu, Dudoit Sandrine, Ng Irene O L, Van De Rijn Matt, Botstein David, Brown Patrick O
Abstract excerpt
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression patterns in HCC compared with those seen in nontumor liver tissues. The expression patterns in HCC were also readily distinguished from those associated with tumors metastatic to liver. The global gene expression...
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