Evaluation of the positional candidate gene CHRNA7 at the juvenile myoclonic epilepsy locus (EJM2) on chromosome 15q13-14.

doi:10.1016/s0920-1211(02)00027-x

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Article

Evaluation of the positional candidate gene CHRNA7 at the juvenile myoclonic epilepsy locus (EJM2) on chromosome 15q13-14.

Epilepsy research - 1 Apr 2002

Taske Nichole L, Williamson Magali P, Makoff Andrew, Bate Louise, Curtis David, Kerr Michael, Kjeldsen Marianne J, Pang Kiang An, Sundqvist Anders, Friis Mogens L, Chadwick David, Richens Alan, Covanis Athanasios, Santos Manuela, Arzimanoglou Alexis, Panayiotopoulos Chrysostomos P, Whitehouse William P, Rees Michele, Gardiner R Mark

Abstract excerpt

A previous study of 34 nuclear pedigrees segregating juvenile myoclonic epilepsy (JME) gave significant evidence of linkage with heterogeneity to marker loci on chromosome 15q13-14 close to the candidate gene CHRNA7 (Hum. Mol. Genet. 6 (1997) 1329). The aim of this work was to further evaluate the putative aetiological role of CHRNA7 in JME within the 34 families originally described, and to assess the...

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PMID: 12049804
DOI: 10.1016/s0920-1211(02)00027-x

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CHRNA7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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