Article
Two brothers with gelatinous drop-like dystrophy at different stages of the disease: role of mutational analysis.
American journal of ophthalmology - 1 Jun 2002
Yoshida Shigeo, Kumano Yuji, Yoshida Ayako, Numa Shin-ichiro, Yabe Nobuyuki, Hisatomi Toshio, Nishida Teruo, Ishibashi Tatsuro, Matsui Takao
Abstract excerpt
PURPOSE: A report of two Japanese brothers with gelatinous drop-like corneal dystrophy, one with and one without the typical gelatinous drop-like region. DESIGN: Interventional case report and observational case report. METHODS: After penetrating keratoplasty, the corneal button, right eye, of the elder brother, 39 years of age, was stained and examined by microscopy. The M1S1 and BIGH3 genes were examined for...
Topics
- Adult
- Antigens, Neoplasm
- Biomarkers, Tumor
- Cell Adhesion Molecules
- Consanguinity
- Cornea
- Corneal Dystrophies, Hereditary
- DNA
- DNA Mutational Analysis
- Epithelial Cell Adhesion Molecule
- Extracellular Matrix Proteins
- Humans
- Keratoplasty, Penetrating