Article
IFN-alpha2b monotherapy in patients with chronic hepatitis C and persistently normal or near normal aminotransferase activity: a randomized, controlled study.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Mar 2002
Tassopoulos Nicholas C, Vafiadis Irene, Tsantoulas Dimitrios, Syrokosta Julia, Hatzis Gregory, Delladetsima Johanna K, Demonakou Maria, Sypsa Vana, Hatzakis Angelos E
Abstract excerpt
To determine the effect of interferon-alpha2b (IFN-alpha2b) on the long-term suppression of hepatitis C virus (HCV) RNA in patients with persistently normal or near normal alanine aminotransferase (ALT) activity, 76 previously untreated patients with serum HCV RNA and ALT levels <1.5 times the upper limit of normal (ULN) were randomized to receive either interferon-alpha2b (IFN-alpha2b) 5 MU three times a week...
Topics
- Adult
- Alanine Transaminase
- Antiviral Agents
- Female
- Follow-Up Studies
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Interferon-alpha
- Male
- Middle Aged