Article
Sequence of a new DR12 allele with two silent mutations that affect PCR-SSP typing.
Tissue antigens - 1 Feb 2002
Zanone R, Bettens F, Tiercy J-M
Abstract excerpt
A new HLA-DR12 allele has been identified in a European Caucasoid bone marrow donor. The DRB1*12012 allele differs from DRB1*12011 by two silent substitutions at codons 72 and 78, two polymorphic positions used for DNA subtyping of the DR12 serotype. The co-occurence of the two nucleotide changes is unique to the DR12 group and results in a new PCR-SSP typing pattern. The complete HLA type of the donor is A24,...
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