Article
Pregnancy and birth complications in autism and liability to the broader autism phenotype.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 May 2002
Zwaigenbaum Lonnie, Szatmari Peter, Jones Marshall B, Bryson Susan E, MacLean Joanna E, Mahoney William J, Bartolucci Giampiero, Tuff Lawrence
Abstract excerpt
OBJECTIVE: To understand better the relationship between pregnancy and birth complications and genetic factors in autism. METHOD: The sample included 78 children with an autism spectrum disorder and 88 unaffected siblings. A standardized interview was used to ask mothers about the pregnancy and birth of each child, and an overall index reflecting freedom from complications (termed "optimality") was determined....
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