Article
A mutation that prevents paramutation in maize also reverses Mutator transposon methylation and silencing.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002
Lisch Damon, Carey Charles C, Dorweiler Jane E, Chandler Vicki L
Abstract excerpt
Both paramutation and Mutator (Mu) transposon inactivation involve heritable changes in gene expression without concomitant changes in DNA sequence. The mechanisms by which these shifts in gene activity are achieved are unknown. Here we present evidence that these two phenomena are linked mechanistically. We show that mutation of a gene, modifier of paramutation 1 (mop1), which prevents paramutation at three...
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